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Gajewski, Thomas F.

One or more keywords matched the following items that are connected to Gajewski, Thomas F.

Item Type	Name
Concept	Lymphocyte Activation
Academic Article	Differential regulation of murine T lymphocyte subsets.
Academic Article	Differential function of intestinal intraepithelial lymphocyte subsets.
Academic Article	B7-1 but not B7-2 efficiently costimulates CD8+ T lymphocytes in the P815 tumor system in vitro.
Academic Article	Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones.
Academic Article	Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice.
Academic Article	Blocked Ras activation in anergic CD4+ T cells.
Academic Article	Biochemical analysis of activated T lymphocytes. Protein phosphorylation and Ras, ERK, and JNK activation.
Academic Article	B7.1 is a quantitatively stronger costimulus than B7.2 in the activation of naive CD8+ TCR-transgenic T cells.
Academic Article	CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Academic Article	Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152).
Academic Article	Transplantation and the CD28/CTLA4/B7 pathway.
Academic Article	Differential activation of murine TH1 and TH2 clones.
Academic Article	T cell development and function in CrkL-deficient mice.
Academic Article	Integrating IL-12 into therapeutic cancer vaccines.
Academic Article	Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase.
Academic Article	Cutting edge: targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells.
Academic Article	Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy.
Academic Article	Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
Academic Article	Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.
Academic Article	Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells.
Academic Article	Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites.
Academic Article	Molecular regulation of T-cell anergy.
Academic Article	Protein kinase Ctheta focusing at the cSMAC is a consequence rather than cause of TCR signaling and is dependent on the MEK/ERK pathway.
Academic Article	Anti-proliferative effect of IFN-gamma in immune regulation. IV. Murine CTL clones produce IL-3 and GM-CSF, the activity of which is masked by the inhibitory action of secreted IFN-gamma.
Academic Article	Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy.
Academic Article	Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.
Academic Article	Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.
Academic Article	Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Academic Article	Costimulatory and coinhibitory receptors in anti-tumor immunity.
Academic Article	Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
Academic Article	Nakahara memorial lecture. Regulation of T lymphocyte responses: interactions among receptors.
Academic Article	Evidence implicating I region-restricted antigen presentation in alloantigen and nominal antigen recognition by a dual-reactive helper T lymphocyte clone.
Academic Article	Murine hepatic accessory cells support the proliferation of Th1 but not Th2 helper T lymphocyte clones.
Academic Article	Regulation of T-cell activation: differences among T-cell subsets.
Academic Article	Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.
Academic Article	Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes.
Academic Article	Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.
Academic Article	Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1.
Academic Article	Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
Academic Article	An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells.
Academic Article	Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-?1 phosphorylation.
Academic Article	Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
Academic Article	Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor.
Academic Article	Formation of a central supramolecular activation cluster is not required for activation of naive CD8+ T cells.
Academic Article	Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level.
Academic Article	Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.
Academic Article	CD40 ligation reverses T cell tolerance in acute myeloid leukemia.
Academic Article	Targeting the tumor microenvironment with interferon-ß bridges innate and adaptive immune responses.
Academic Article	Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction.
Academic Article	STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article	Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.
Academic Article	Innate and adaptive immune cells in the tumor microenvironment.
Academic Article	Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.
Academic Article	Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy.
Academic Article	NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.
Academic Article	The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment.
Academic Article	Impact of oncogenic pathways on evasion of antitumour immune responses.

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Lymphocyte Activation